Anabolic steroid abuse is associated with increased systolic hypertension riskMost medical texts that discuss the side effects of anabolic steroids suggest that the reason they may increase blood pressure is their sodium-retention properties. One possible side effect of high-dose regimens of anabolic steroids is high blood pressure, or hypertension. Having high blood pressure weight gain and testosterone cream damages the endothelium, or inner lining, of arteries, which sets you up for atherosclerosis, a narrowing of arteries that can result in a heart attack or stroke. High-dose steroid anabolic steroids cause high blood pressure inhibits the enzyme beta hydroxylase, which leads to excessive production of deoxycorticosterone, a mineralocorticoid in the adrenal glands, and, in due course, sodium and water retention. The scenario can also lead to elevated blood pressure.
Page not available
Most medical texts that discuss the side effects of anabolic steroids suggest that the reason they may increase blood pressure is their sodium-retention properties.
One possible side effect of high-dose regimens of anabolic steroids is high blood pressure, or hypertension. Having high blood pressure also damages the endothelium, or inner lining, of arteries, which sets you up for atherosclerosis, a narrowing of arteries that can result in a heart attack or stroke. High-dose steroid use inhibits the enzyme beta hydroxylase, which leads to excessive production of deoxycorticosterone, a mineralocorticoid in the adrenal glands, and, in due course, sodium and water retention.
The scenario can also lead to elevated blood pressure. A new study suggests another reason that anabolic steroids can elevate blood pressure. The subjects had been training for at least two years.
Those in the steroid group self-administered the drugs for at least one month prior to the study. The researchers wanted to know whether using steroids increased the release of sympathetic hormones, such as epinephrine and norepinephrine. The steroid users experienced increased muscle sympathetic nerve activity along with reduced forearm blood flow compared to those not using the drugs. They also had higher hour blood pressure readings. Animal-based studies have shown that giving the animals high doses of stanozolol, sold as Winstrol, increases their blood pressure.
Past studies have demonstrated that anabolic steroids may boost blood pressure by interfering with the activity of nitric oxide, which is produced in the lining of blood vessels and dilates, or opens, the vessels—obviously something that would lower blood pressure. Early studies of testosterone found that it could enhance the vascular response to norepinephrine.
All anabolic steroids are synthetic versions of testosterone, yet most cardiovascular side effects linked to their use subside when people stop taking them. On the other hand, the news is grave for those who elect to stay on steroids without a break. They are likely at higher risk for heart attack and stroke.
That said, the effect is associated with high-dose steroid use and has nothing to do with testosterone-replacement therapy. In people who are deficient in testosterone, the hormone helps prevent high blood pressure. While the medical literature suggests that the primary side effects linked to high-dose anabolic steroid use involve the cardiovascular system and the liver—particularly when it comes to oral steroids—case studies occasionally emerge that document some unusual side effects.
Do you want to be one of the rare cases for whom side effects prove fatal? Bodybuilders who inject themselves with steroids can be susceptible to a variety of problems.
Infections, or abscesses, at the injection site are one example—caused either by using a nonsterile needle or not paying attention to antiseptic procedures, such as ensuring that the injection area is clean and sterile.
Foreign substances could be contained in the injected drug itself. Veterinary prescriptions can contain impurities that cause localized reactions in human users. Sharing needles, meanwhile, is nothing short of moronic—you leave yourself open to hepatitis and HIV. A new case study discusses cases where anabolic steroid users developed suspicious masses at injection sites. When tissue samples were viewed, the initial diagnosis was consistent with a tumor because of the appearance of the sample.
The primary purpose of the case report was to warn physicians to be wary when making an initial diagnosis of a mass found in a steroid user. That, they say, will prevent unnecessary surgery related to tumor removal. Far more alarming was the case study involving a year-old man who showed up at a hospital complaining of severe sore muscles.
The extent of the enzyme elevation suggested rhabdomyolysis, or excess muscle breakdown. He was treated with cortisone drugs, but three days later his enzyme count had nearly doubled, indicating that whatever was causing the problem was progressing. He was then given intravenous cortisone, but his throat appeared to be caving in, so they transferred him to the intensive care unit.
He was there for 37 days. During that time he went into kidney failure, related to the excess muscle breakdown occurring in his body, and was put on a kidney machine. Still, his muscle enzymes continued to rise. He then developed a number of complications that did not respond to treatment, and he died of cardiac arrest.
The interesting and mysterious aspect of that case is that the man showed no evidence of any infection or inflammation that would provoke such extreme muscle destruction. He showed no traces of bacterial or viral infection or any autoimmune reaction. So what did the doctors attribute his tragic death to?
I would suggest that if the death really had been caused by anabolic steroids and it happened more often, that would dissuade potential steroid users more than any antidrug campaign. The final case study involved a year-old male pro bodybuilder who went into surgery because of a malignant tumor found on his chest wall.
Of course, it was administered in hospital conditions by trained doctors. The doctors gave him drugs that raised his blood pressure, and he was stabilized; the surgery continued.
Even though the bodybuilder had last used steroids 12 years prior to the surgery, the doctors attributed the surgical crisis to past steroid use. Several factors came into play in that surgery: The purpose of this case study was to warn surgeons to take a bodybuilding history into account—particularly one that involved heavy drug use for years—when setting up an anesthesia surgical drug protocol.
The unstated warning was that athletes who have been on high-dose steroid regimens may present a surgical risk that requires careful monitoring.
Jerry Brainum has been an exercise and nutrition researcher and journalist for more than 25 years. Abnormal neurovascular control in anabolic androgenic steroid users.
Med Sci Sports Exerc. Factitial soft tissue pseudotumor due to injection of anabolic steroids: A report of 3 cases in 2 patients. Anabolic androgenic steroid induced necrotising myopathy. Severe hemodynamic instability during general anesthesia in a professional bodybuilder.
J Cardiothor Vascul Anesth. You must be logged in to post a comment Login. You must be logged in to post a comment. Expert advice for over athletes about training, supplementation, nutrition, hormones, and more. We pick our five favorite natural testosterone boosters. Some of the most dubious products in the history of supplements have been testosterone boosters.
So when a product like VitalGenix A new study performed by researchers at the University Fish oil provides tremendous health benefits from improving mood to battling dry skin but most of us take it for its Whey protein is king when it comes to initiating protein synthesis and improving body composition, and with a few small tweaks If your goal is to have ripped abs, a muscular body, and long-lasting sex, then your total testosterone levels should be Hormones November 7, You must be logged in to post a comment Login Leave a Reply Cancel reply You must be logged in to post a comment.
Newsletter The latest, greatest training info and research delivered to your online mailbox every week and it's FREE. It's your road to radical results. Find us on Facebook. Subscribe to Our Channel. IM Ask Us Anything 2 Expert advice for over athletes about training, supplementation, nutrition, hormones, and more.
Sharon Ortigas June 30, Iron Man Magazine September 5, VitaliGenix T10 by MuscleTech Some of the most dubious products in the history of supplements have been testosterone boosters. Iron Man Magazine July 18, Iron Man Magazine June 7, Transform your fat Fish oil provides tremendous health benefits from improving mood to battling dry skin but most of us take it for its Iron Man Magazine June 4, Turbocharge your Whey Whey protein is king when it comes to initiating protein synthesis and improving body composition, and with a few small tweaks Iron Man Magazine June 1, Iron Man Magazine May 25, Iron Man Magazine May 19,