Mast cell activation and clinical outcome in pediatric cholelithiasis and biliary dyskinesiaThe current study was undertaken to determine the degree of activation of gallbladder mucosal mast cells, whether mast cell MC density or activation differ between patients with and without a p daniel mast clinical response to cholecystectomy, and whether either density or activation correlate with gallbladder emptying. Fifteen biliary dyskinesia BD and 13 p daniel mast cholelithiasis CL patients undergoing cholecystectomy were prospectively enrolled. Gallbladder wall MC density by immunohistochemistry and activation by electron microscopy were determined. Clinical response was evaluated 30 days post-cholecystectomy on a 5-point Likert-type scale. The overall degranulation indices were
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