Cortisone/corticosteroids and weight
Medically reviewed on Apr 26, by C. Prednisone Rayos is a corticosteroid - often called a steroid for short. These types of steroids are different to the anabolic steroids abused by body builders or athletes wishing to gain a competitive edge.
Corticosteroids come in two types - glucocorticoids and mineralocorticoids. Prednisone is a glucocorticoid. Glucocorticoids have a powerful anti-inflammatory and anti-allergic effect and mimic cortisol which is a naturally occurring substance released by our adrenal glands in response to inflammation and stress. Prednisone controls inflammation by suppressing our immune system and is four times more potent than cortisol at decreasing inflammation.
However, prolonged use can cause immunosuppression, muscle wasting, bone changes, fluid shifts, and personality changes. For these reasons, prednisone is usually only prescribed short-term.
The discovery of prednisone in the s by Arthur Nobile revolutionized the treatment of arthritis. Since then, it has been the used in the treatment of dozens of other conditions, such as asthma , allergies , lupus , multiple sclerosis , ulcerative colitis , and numerous skin conditions.
Prednisone has helped save the lives of hundreds of thousands of people. But like every drug, its good points need to be weighed up against its not-so-good points.
Rayos is a common brand name, and several generics are available. Your drugstore may sometimes stock different brands from time to time, which may mean that sometimes the colour or look of your prednisone may change.
Check with your pharmacist if you are unsure why there is a change. Alternatively, you can use our pill identification wizard.
Prednisone dosing may be complicated and not uncommonly start with a higher dose which is gradually reduced over days to weeks. There is a fine line between too much or too little prednisone. Always read the label or talk with your pharmacist about the schedule your doctor has recommended.
Never assume it will be the same as what you had last time or what a friend or family member is prescribed. Never take more prednisone than your doctor has recommended.
Never stop prednisone suddenly if you have been taking it for a long period of time. Never start another course of prednisone without first discussing this with your doctor. Always follow all instructions. Prednisone can irritate the lining of your stomach and should always be taken with a meal.
If your stomach still feels sore after taking prednisone with food, try taking an antacid. If the discomfort persists or gets worse, talk to your doctor.
You are also more likely to get stomach ulcers if you take prednisone in combination with anti-inflammatories or aspirin. If you are prescribed these medicines, ask your doctor about protective agents that can reduce this risk. Adrenal gland suppression is when your body stops producing cortisol, and it can happen with continual dosing of prednisone. If you are on daily prednisone, experts recommend taking the dose in the morning, to reduce this risk.
Taking prednisone too late in the evening can cause sleeplessness and insomnia, too. Make sure you also take your dose of prednisone with food, and just FYI, grapefruit juice has no effect on prednisone.
Prednisone has long-lasting effects and is usually prescribed once daily. Occasionally, people on higher dosages are instructed to take it twice a day for short periods of time before dropping down to just a single dose. Rather it means that it can just take a while to kick start your body back into producing cortisol again, if you have been on prednisone for longer than two weeks.
Withdrawal symptoms can range from severe fatigue to weakness, body aches, joint pain, and difficulty sleeping. Talk to your doctor about slowly stopping prednisone over a period of several weeks if you need to discontinue its use. Infections are more common while on prednisone because it suppresses your immune system.
This makes it harder for your body to fight off infection. In some circumstances, prednisone can help pre-existing infections, particularly those caused by yeasts or fungi, to spread. Symptoms of an infection may also not be as obvious or typical while you are on prednisone. While you are taking prednisone you should take common-sense precautions to reduce your risk of infection - such as washing your hands often and avoiding people who are sick, or those with viral illnesses such as chickenpox or measles.
Tell your doctor straight away if you develop any sort of infection, including eye infections or thrush, while you are taking prednisone. Long-term use of prednisone may lead to bone loss and osteoporosis. It can cause changes in the distribution of body fat which together with fluid retention and weight gain may give your face a moon-like appearance.
Stretch marks, skin thinning, and excessive facial hair growth are also not uncommon. Women who are pregnant or planning a pregnancy should let their doctor know before they take prednisone, and it is not recommended in women who are breastfeeding a baby. Children are particularly susceptible to prednisone's side effects.
Prednisone may suppress growth and development, an unfortunate effect that may be helped by alternate day treatment or growth hormone therapy. Prednisone may also cause sleeplessness and affect your moods. People with diabetes may find their blood glucose control is not as good as it usually is while they are taking prednisone.
It is a good idea to wear a medical alert tag or carry a Steroid Card if you need to take prednisone long-term. Prednisone makes you hungry and weight gain is a common side effect. Fat deposits may occur around your abdomen,face or back of your neck. Fluid retention can also occur and may manifest as leg swelling and a sudden jump in your weight on the scales. The higher the dose and the longer the treatment, the more likely you are to put on weight.
You can control fluid retention by eating a diet low in sodium and eating more foods that contain potassium such as bananas, apricots, and dates. A diet high in protein and low in carbohydrates may make you feel fuller for longer, making you less likely to overeat. Both prednisone and prednisolone are man-made glucocorticoids.
They are used to treat similar conditions and are generally considered equally effective. However, in people with liver disease, prednisolone is usually preferred. This is because prednisone needs to be converted by liver enzymes into prednisolone before it can work. Price wise, prednisone is usually much cheaper than prednisolone.
Prednisone can interact with a number of different drugs, including OTC and some herbal preparations. Let your doctor know about all the medications you take. If you are worried that some of your medicines may be interacting, talk with your doctor or pharmacist. Alternatively, you can use our drug interaction checker.
The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to receive email notifications whenever new articles are published. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
To view content sources and attributions, please refer to our editorial policy. We comply with the HONcode standard for trustworthy health information - verify here. While experts may not know the exact cause of some of these conditions, they do know that they are all associated with inflammation. Prednisone helps in the treatment of these conditions by dampening down this inflammation. Prednisone Increases Your Risk of Infection.
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