fluphenazine decanoateUpdated November 30, If you are a consumer or patient please fluphenazine decanoate prescribing information this best tren enanthate cycle. Fluphenazine decanoate is the decanoate ester of fluphenazine decanoate prescribing information trifluoromethyl phenothiazine derivative. It is a highly potent behavior modifier with a markedly extended duration of effect and has the following structural formula:. Fluphenazine Decanoate Injection, USP is available as a clear, pale yellow solution for intramuscular IM or subcutaneous SC use providing 25 mg fluphenazine decanoate per mL in a sesame oil vehicle with 12 mg benzyl alcohol as a preservative. The basic effects of fluphenazine decanoate appear to be no different from those of fluphenazine hydrochloride, with the exception of duration of action.
Fluphenazine decanoate Monograph for Professionals - jmhw.info
Prolixin, Fluphenazine Decanoate, is an antipsychotic medication used to treat Schizophrenia. Uses, dosage, side effects. Prolixin Fluphenazine Decanoate is a phenothiazine, an antipsychotic medication, used to treat emotional disorders such as schizophrenia. It may also be used to treat other conditions as determined by your doctor. This medicine is usually administered as an injection at your doctor's office or a clinic. The onset of action generally appears between 24 to 72 hours after injection, and the effects of the drug on psychotic symptoms become significant within 48 to 96 hours.
Amelioration of symptoms then continues for 1 to 8 weeks with an average duration of 3 to 4 weeks. There is considerable variation in the individual response of patients to this depot fluphenazine and its use for maintenance therapy requires careful supervision. Fluphenazine Decanoate Prolixin, Permitil, Modecate is indicated for the treatment of schizophrenia. Patients who have shown hypersensitivity to other phenothiazines, including fluphenazine, should not be given fluphenazine decanoate.
Phenothiazines should not be used in patients receiving large doses of hypnotics, due to the possibility of potentiation. Severe adverse reactions requiring immediate medical attention may occur and are difficult to predict. Therefore, the evaluation of tolerance and response, and establishment of adequate maintenance therapy, require careful stabilization of each patient under continuous, close medical observation and supervision.
Interference with Cognitive or Motor Performance: Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Do not become overheated in hot weather, during exercise, or other activities since heat stroke may occur while you are using this medicine. This medicine may cause increased sensitivity to the sun.
Avoid exposure to the sun or sunlamps until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. Safety during pregnancy has not been established. The drug should not be administered to women of childbearing potential, particularly during the first trimester, unless, in the opinion of the physician, the expected benefits outweigh the potential risks to the fetus.
Phenothiazines should be used with caution in patients with a history of convulsive disorders since grand mal seizures have been known to occur. Since hypotension and ECG changes suggestive of myocardial ischemia have been associated with the administration of phenothiazines, fluphenazine decanoate should be used with caution in patients with compensated cardiovascular or cerebrovascular disorders.
Before using this medicine, inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. This includes guanethidine and medicines used to treat depression and bladder or bowel spasms. Inform your doctor of any other medical conditions including depression, seizure disorders, allergies, pregnancy, or breast-feeding.
Use with other drugs: The effects of atropine or other drugs with similar action may be potentiated in patients receiving phenothiazines because of added anticholinergic effects. Paralytic ileus, even resulting in death, may occur especially in the elderly. Fluphenazine decanoate should be used cautiously in patients exposed to extreme heat or phosphorus insecticides.
Side effects that may go away during treatment, include drowsiness, dizziness, nasal congestion, blurred vision, dry mouth, or constipation. If they continue or are bothersome, check with your doctor. Symptoms of overdose may include restlessness, muscle spasms, tremors, twitching, deep sleep or loss of consciousness, and seizures. Of the cases of deliberate or accidental overdose involving fluvoxamine maleate reported, there were 19 deaths.
Of the 19 deaths, 2 were in patients taking fluvoxamine maleate alone and the remaining 17 were in patients taking fluvoxamine maleate along with other drugs. If you or someone you know may have used more than the recommended dose of this medicine, contact your local poison control center or emergency room immediately. No further injections should be given until the patient shows signs of relapse and the dosage then should be decreased.
An unobstructed airway should be established with maintenance of respiration as required. Severe hypotension calls for the immediate use of an i. Extrapyramidal symptoms may be treated with antiparkinsonian agents. Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions.
Keep this medicine out of the reach of children. Your doctor may increase your dose if needed. However, the dose is usually not more than 20 mg a day. The initial recommended dose is 2. An initial dose of However, an initial test dose of 2. Patients can usually be controlled with 25 mg or less, every 2 to 3 weeks. Although doses greater than 50 mg are usually not necessary, doses up to mg have been used in some patients.
If doses greater than 50 mg are necessary, the next dose and succeeding doses should be increased in increments of While the response to a single injection lasts usually 2 to 3 weeks, it may last for 4 weeks or more.
Each mL of injectable solution contains: Fluphenazine decanoate 25 mg in sesame oil with benzyl alcohol 1. Vials of 5 mL. Fluphenazine decanoate mg in sesame oil with benzyl alcohol 1.
Ampuls of 1 mL. The information in this monograph is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects. This information is generalized and is not intended as specific medical advice.
If you have questions about the medicines you are taking or would like more information, check with your doctor, pharmacist, or nurse. Psychiatric Medications Pharmacology Homepage.
Prolixin, Permitil, Modecate Generic Name: Pluphenazine Decanoate Prolixin, Fluphenazine Decanoate, is an antipsychotic medication used to treat Schizophrenia. What is an Eating Disorder? Mental Health Newsletter Sign up for the HealthyPlace mental health newsletter for latest news, articles, events.
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